I: Morphology.- Morphological Correlates for Transmitter Synthesis, Transport, Release, Uptake and Catabolism: A Study of Serotonin Neurons in the Nucleus Paragigantocellularis Lateralis.- Comments on the Morphology of Inhibitory Axons.- Ultrastructural Analysis of Axo-Dendritic Initial Collateral Terminals of a Feline Spinocervical Tract Neurone, Stained Intracellularly with Horseradish Peroxidase.- Electron Cytochemistry of GABA-Transaminase in Rat Cetebellar Cortex, and Evidence for Multimolecular Forms of the Enzyme.- II: Electrophysiology and Neuropharmacology.- Pre- and Non-Synaptic Activities of GABA and Related Amino Acids in the Mammalian Nervous System.- Quantitative Studies of Iontophoretically Applied Excitatory Amino Acids.- Interactions of Central Depressants with Amino Acids and Their Antagonists.- III: Localization.- Critical Evaluation of the Use of Radioautography as a Tool in the Localization of Amino Acids in the Mammalian Central Nervous System.- Transmitters in the Basal Ganglia.- Comments on the Localization of Neurotransmitters in the Basal Ganglia.- Localization of Transmitter Amino Acids: Application to Hippocampus and Septum.- Glutamate Concentration in Individual Layers of the Rabbit Hippocampus.- The Effect of Intrahippocampal Administration of ?-Aminobutyric Acid (GABA).- Neurotransmitters in the Amygdala: A Brief Review.- GABA Markers in the Hypothalamus: Topographical Distribution and Origin.- Identified Aplysia Neurons with Rapid and Specific Glycine Uptake.- IV: The Visual System.- Neurotransmitters in the Avian Visual System.- Neurotransmitters of the Mammalian Visual System.- The Localization and Metabolism of Neuroactive Amino Acids in the Retina.- Light-Induced Release of Amino Acids from the Retina.- Classification and Location ofNeurons Taking up 3H-GABA in the Visual Cortex of Rats.- V: Uptake, Synthesis and Release.- GABA Agonists and Uptake Inhibitors of Restricted Conformations: Structure-Activity Relations.- Muscimol Analogues Injected into Substantia Nigra: A Valuable New In Vivo Model for GABA-Ergic Drugs.- Uptake, Exchange and Release of GABA in Isolated Nerve Endings.- Cis 3-Aminocyclohexane Carboxylic Acid, a Selective Inhibitor and Substrate for the Neuronal GABA Uptake Process.- Properties of the Accumulation of D-[14C]Aspartate into Rat Cerebral Crude Synaptosomal Fraction.- The Effect of Glutamate on the Structure and K+-Transport of Synaptosomes.- On the Metabolic and Intrasynaptic Origin of Amino Acid Transmitters.- Glutamate as a CNS Neurotransmitter: Properties of Release, Inactivation and Biosynthesis.- Role of GABAergic and Glycinergic Transmissions in the Substantia Nigra in the Regulation of Dopamine Release in the Cat Caudate Nucleus.- The Interaction Between GABAergic Drugs and Dopaminergic Stimulants.- Glutamate Decarboxylase, Properties and the Synaptic Function of GABA.- The Possible Involvement of GABA and its Compartmentation in the Mechanism of Some Convulsant and Anticonvulsant Agents.- VI: Receptor Binding.- The GABA Receptor Assay: Focus on Human Studies.- 3H-GABA Binding to Membranes Prepared from Post-Mortem Human Brain: Pharmacological and Pathological Investigations.- Studies on the Gamma Aminobutyric Acid Receptor/Ionophore Proteins in Mammalian Brain.- Comparison of 3H-Muscimol and 3H-GABA Receptor Binding in Rat Brain.- GABA Receptor in Rat Brain: Demonstration of an Antagonist Binding Site.- A Study of the GABA Receptor Using 3H-Bicuculline Methobromide.- GABA Receptors and Phospholipids.- Second Messenger Responses and Regulation of High Affinity Receptor Binding to Study Pharmacological Modifications of GABAergic Transmission.- VII: Functional and Metabolic Aspects.- Glycine: Inhibition from the Sacrum to the Medulla.- Taurine and Other Sulphur Containing Amino Acids: Their Function in the Central Nervous System.- A Functional Role for Amino Acids in the Adaptation of Tissues from the Nervous System to Alterations in Environmental Osmolality.- Isolation and Biochemical Characterization of Morphologically Defined Structures, Including Cell Types, From the Cerebellum.- Glial Cells and Amino Acid Transmitters.- Interactions Between Neurotransmitters and Astroglial Cells.- Amino Acid Precursors: Their Transport into Brain and Initial Metabolism.- Metabolic Compartmentation of the Glutamate-Glutamine System: Glial Contribution.- Compartmentation of Amino Acids in Brain: The GABA-Glutamine-Glutamate Cycle.- Computer Modeling as an Aid to Understanding Metabolic Compartmentation of the Krebs Cycle in Brain Tissue.