Xinzhong Dong,
Brian Kim,
Brian S. Kim,
Taylor Follansbee
e.a.
Elsevier Science
e druk, 2026
9780443341724
The Itch Spectrum
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2026
ISBN13: 9780443341724
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
The Itch Spectrum: The Neurological and Immunological Basis of Itch and Dermatological Disorders covers the latest research on the itch signalling pathway from the skin to the brain. With a multidisciplinary approach, this book will cover the mechanisms underlying the sensation of itch from the fields of neuroscience, immunology, genetics, and dermatology as they have intersected in the study of one somatosensory system. The purpose of this comprehensive reference is to summarize the revelatory discoveries in the field of itch and provide a comprehensive overview of what is known about this remarkable sensation and how various pathologies contribute to chronic pruritis.
Specificaties
Inhoudsopgave
Section 1: Preclinical Perspective<br>1. Historical perspective of itch research<br>2. Primary afferent neurons involved with itch<br>3. Receptors of itch: GPCRs<br>4. TRP channels for itch<br>5. Ion channels for itch<br>6. Neuroimmune interactions in itch<br>7. Cytokine in itch induction and modulation<br>8. Mast cells and itch<br>9. Bacteria and Virus Induced itch<br>10. Spinal pathways and projection neurons for itch<br>11. Spinal Glia–Neuron interactions in chronic itch<br>12. Central targets for itch<br>13. Aversive and reward circuits in itch processing<br>14. Descending modulation of itch<br>15. Neural coding of itch versus pain<br>16. Mechanical itch and alloknesis<br>17. Mouse models for acute itch<br>18. Mouse models of chronic itch<br>19. Mucosal itch<br>20. Drug induced itch<br>21. Conservation of itch across species<br><br>Section 2: Clinical Perspectives<br>22. Epidemiology of itch<br>23. Atopic dermatitis<br>24. Psoriasis<br>25. Prurigo nodularis<br>26. Cholestatic and uremic itch<br>27. Neuropathic itch<br>28. Itch caused by connective tissue diseases<br>29. fMRI and itch<br>30. Recent advances for drug targets to treat itch