Adam E.M. Eltorai,
Jeffrey A. Bakal,
Maleeha Ahmad
Elsevier Science
e druk, 2025
9780323905091
Translational Neurosurgery
Specificaties
Paperback, blz.
|
Engels
Elsevier Science |
2025
ISBN13: 9780323905091
Rubricering
Onderdeel van serie
Handbook for Designing and Conducting Clinical and Translational Research
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Translational Neurosurgery provides a comprehensive overview reflecting the depth and breadth of the field of translational research focused on neurosurgery, with input from a distinguished team of basic and clinical investigators. It covers the principles of evidence-based medicine and applies these principles to the design of translational investigations, helping researchers navigate challenging considerations in study design and implementation.
This book is a valuable resource for neurosurgeons and neurosurgery investigators who want to understand more about translational research, and also for basic scientists interested in translating their research into clinical practice.
Specificaties
Inhoudsopgave
Section 1: Introduction<br>1. Translational Process<br>2. Scientific Method<br><br>Section 2: Pre-Clinical<br>4. What problem are you solving?<br>5. Types of interventions<br>6. Drug testing<br>7. Device discovery and prototyping<br>8. Diagnostic testing<br>9. Artificial Intelligence<br><br>Section 3: Statistical Principles<br>10. Basic statistical principles<br>11. Distributions<br>12. Hypotheses and error types<br>13. Power<br>14. Continuous variable analyses<br>15. Categorical variable analyses: Chi-square, fisher exact, Mantel hanzel<br>16. Analysis of variance<br>17. Correlation<br>18. Basic science statistics<br>19. Sample Size<br>20. Statistical Software<br><br>Section 4: Clinical: Study Types<br>21. Outcome measurements: What data is being collected and why?<br>22. Case series: Design, measures, classic example<br>23. Case-control study: Design, measures, classic example<br>24. Cross-section study: Design, measures, classic example<br>25. Longitudinal study: Design, measures, classic example<br>26. Meta-analysis: Design, measures, classic example<br>27. Qualitative methods and mixed methods<br><br>Section 5: Clinical Trials<br>28. Randomization and Multicentric Considerations in Clinical Trials<br>29. Nonrandomized Control<br>30. Historical Control<br>31. Study Types with Design, Measures, Classic Example<br>32. Blinding: Who and How?<br>33. Adaptive: Design, measures, classic example<br>34. Phase 0 Trials: Window of Opportunity<br>35. Registries, Phases of Clinical Trials, IDEAL Framework<br><br>Section 6: Regulatory Basics<br>36. FDA overview<br>37. IND<br>38. Devices<br>39. Radiation-emitting Electronic Products<br>40. Biologics<br>41. Combination Products<br>42. A Brief Overview of the FDAs Involvement in the Regulation of Dietary Supplements<br>43. Cosmetics<br>44. CMC and GxP<br>45. Non-US regulatory<br>46. Post-Market Drug Safety Monitoring<br>47. Post-Market Device Safety Monitoring<br><br>Section 7: Public Health<br>48. Public Health<br>49. Epidemiology<br>50. Factors<br>51. Good Questions<br>52. Population- and Environmental-specific Considerations<br>53. Healthcare Institutions and Systems<br>54. Public Health Institutions and Systems<br>55. Presenting Data