I. Methods for Analyzing Bone Metabolism — Progress and Critical Remarks.- Morphological and Crystallographic Analysis of Bone Mineral.- Quantitative Aspects of Calcium Metabolism and Homeostasis.- A Time-Varying Model for Calcium Metabolism Including Diurnal Variations.- Quality Control and Correlations of Clinical Methods for Studying Metabolic Bone Disease.- Morphometric Microdensity Studies of Hard Tissue Sections, Utilising Optical Density Contour Maps and Associated Area Coordinated Computerised Data.- On Calcium Metabolism during Immobilization.- Limitations in Bone-Mass Measurements with 241Am.- Intestinal Absorption and Retention of Calcium Measured by Whole-Body Counting.- II. Pharmacology and Metabolism of Vitamin D.- Studies on the Metabolism, Mode of Action and Pharmacology of Vitamin D and Related Analogs.- Vitamin D-Dependent Calcium Binding Protein of Rat Renal Cortex.- The Effect of Disodium Ethane-1-hydroxy-1, 1-Diphosphonate on the Metabolism of Vitamin D.- The Effect of Estrogen on Calcium Binding Protein Activity in Odentogenic Epithelium of the Rat.- Effect of Vitamin D on the Bone in Anticonvulsant Osteomalacia.- The Effect of Vitamin D3 on Lanthanum Absorption: Suggestive Evidence for a Shunt Path.- The Effects of Cyclic AMP, Hormones and Ions on the Conversion of 25-Hydroxycholecalciferol (25-HCC) to 1,25-Dihydroxycholecalciferol (1,25-DHCC) in Isolated Chick Kidney Tubules.- Extrarenal Metabolism of High Doses of 25-(OH)-D3: a New Active Metabolite.- III. Metabolism and Action of Fluoride.- Fluoride and its Relation to Bone and Tooth.- Absorption, Distribution in Body Fluids, and Bioavailability of Fluoride.- Bone — Body Fluid Fluoride Balance.- Possible Systemic Effects Following the Ingestion of Low Doses of Fluoride.- Effects of Bone Fluoride on Bone Resorption and Metabolism.- Urine Fluoride Levels Following Ingestion of Fluoridated Domestic Salt over Three Years.- Fluoridation of Drinking Water and Bone Mineral Content, Analyzed by Monochromatic (125I) Radiation Absorptiometry.- Effects of Supply and Withdrawal of Fluoride on the Concentration of Fluoride and Glycosaminoglycans in Cortical Bone from Rabbits.- Histological Bone Changes after Long-Term Treatment with Sodium Fluoride.- Long-Term Experience with Fluoride and Fluoride Combination Treatment of Osteoporosis.- IV. Collagen Structure and Calcification.- Collagen Structure and Calcification.- Calcification of Collagenous Material in vitro as a Model System for Biological Calcification.- Further Investigations on the Function of the Osteonic Lamellae According to Collagen and Crystallite Orientation.- The Lability of Aldimine Crosslinks on Dissolution of Chicken Bone Collagen by Protein Denaturants.- Comparison of Ca, P and S Levels in Predentine and Tendon.- The Role of Lysyl Residue in Collagen Structure with Calcification and Aging.- Evidence for a Role of Lysozyme in Endochondral Calcification.- The Formation of Bone Mineral.- V. Biochemistry and Histochemistry of Bone Disease.- Biochemistry of Bone Diseases.- Tetracycline Staining of Bone in Normal and Pathological States.- Biochemical Determinations in Serum and Bone Homogenates from Patients with Femurhead Necroses.- A Clinical and Biochemical Survey of Osteogenesis Imperfecta with Evidence for a Generalised Collagen Defect.- Analysis of Tissue PO2 and PCO2 in Healing Bone.- VI. Therapeutical Aspects of Bone Diseases.- Effect of Various Therapies on Bone Loss in Women.- Effect of Calcitonin in Paget’s Disease.- Biochemical and Radiological Observations in Patients with Osteitis Deformans Treated with Synthetic Human Calcitonin.- Influence of a Diphosphonate and 1,25-Dihydroxycholecalciferol on Calcium Metabolism.- Effect of Various Doses of Disodium Ethane-1 -Hydroxy-1,1 -Diphos- phonate (Sodium Etidronate, EHDP) on Suppression of the Biochemical and Histological Abnormalities in Paget’s Disease of Bone.- Different Behavior of 45Ca and 89Sr in Chronic Uremia in the Rat.- The Effect of 1,25-Dihydroxycholecalciferol in Patients with Vitamin D Resistant States (Chronic Renal Failure, Familial Hypophosphatemia, Gluten Sensitive Enteropathy and Hypoparathyroidism).- Treatment of Renal Osteodystrophy Using Vitamin D or High Dialysate Calcium Concentration.- The Effects of Calcium Supplementation of the Diet on Bone Mass in Women.- VII. Parathyroid Hormone and Calcitonin.- Chemical and Biologic Studies of Parathyroid Hormone, Proparathyroid Hormone and Fragments of Parathyroid Hormone.- Parathyroid Hormone: Structure and Immunoheterogeneity.- Immuno-Reactive Parathyroid Hormone during EDTA Infusion in Chronic Renal Failure.- Preliminary Studies on the Effect of Calcium on the Enzymatic Degradation of Human Calcitonin in the Dog.- Factors Determining the Calcitonin Response in Man.- Separation of the Hypocalcemic and Hypophosphatemic Effects of Calcitonin.- VIII. Varia.- Influences of Endogenous Parathyroid Hormone upon Development and Treatment (Calcium, Calcitonin, Sodium Fluoride) of Experimental Bone Atrophy.- Quantitative Analysis of Bone Changes in Hypercalcitonism (C-Cell Carcinoma).- Intestinal Calcium Absorption 0-30 Years Post Gastrectomy; Study with a Double Isotope Ratio Technique.- The Morphology of the Intestinal Calcium Excretion by the Paneth Cell of Rat, Mouse and Man.- Frictional Ablation — a Neglected Factor in the Mechanisms of Hard Tissue Destruction?.- Tumoral Calcinosis with Hyperphosphatemia.- Chronic Effects of Parathyroid Hormone Infused to Dogs at Near-Physiological Rates.- The Calcium Orthophosphate Solubilities as Represented by a Model in Three Dimensions.- Index of Authors.