I. Pathophysiologic Aspects of Tumor Development.- Cellular Kinetics of Malignant Tumors.- Fetal Patterns in Adult Rat Liver Undergoing Reparative and Neoplastic Growth.- Immunologic Studies on Rat Bowel Carcinomas.- Discussion.- II. Clinical Significance of Immunologic Tests for Tumor Diagnosis.- 1. Tumor-Associated Antigens.- Clinical Significance of Carcinofetal Antigens with Special Reference to CEA, AFP, and Related Substances.- Immunodiagnosis of Gastric Cancer and Related Diseases; Deletion, Neoantigen, and Nonspecific Factors.- Humoral and Cellular Immune Reactions to CEA.- Tumor-Associated Antigens in Bronchogenic Carcinoma.- Tumor-Associated Antigens and Immunity in Prostatic Carcinoma.- Expression of Tumor-Associated Surface Antigens and Their Correlation to Parameters of Malignancy in Human Malignant Melanoma.- Discussion.- 2. Cell-Mediated Immune Reactions.- Correlation Between Nonspecific Immune Competence and Clinical Outcome of Breast, Colon, and Stomach Cancer.- Immunocompetence Testing in Patients with One of the Common Operable Cancers — A Review.- Significance and Mechanism of T-Cell Depression in Cancer.- Cell-Mediated Immune Reactions in Patients with Colon Carcinoma.- Significance of Spontaneous Lymphocyte-Mediated Cytotoxicity (SLMC) in Cancer Patients and Control Persons.- Human Tumor-Lymphocyte Interaction in Vitro: Comparison of the Results With Autologous Tumor Stimulation (ATS) and Lymphocytotoxicity (ALC).- Lymphocyte Cytotoxicity in Melanoma Patients Undergoing Immunotherapy.- Prediction of Recurrent Melanoma by Variations in the Strength of Anti-Tumor Immunity.- Tumor Diagnosis Using Electrophoretic Mobility Test (EMT).- Discussion.- Discussion.- III. Immunotherapeutic Approaches.- The Role of Immunotherapy in the Treatment of Malignant Melanoma.- Tumor Immunotherapy — Experimental Evaluation and Clinical Prospects.- Adjuvant Immunotherapy of Stage II Malignant Melanoma: Autologous Tumor Antigen Plus BCG.- Search for the Role of Immunotherapy with Corynebacterium Parvum Intrapleurally in Operable Bronchial Non-Small-Cell Carcinoma The Ludwig Lung Cancer Collaborative Study Group.- Discussion.- Quantitative and Functional Studies of Lymphocyte Subpopulations During Adjuvant Chemo(immuno)therapy in Patients With Breast Cancer.- Discussion.- Interaction Between Levamisole and an Immunoregulatory Serum Component: Possible Mode of Action of Levamisole as an Immune Modulating Substance.- Role of an Immunoregulatory Serum Component in Human Mixed Lymphocyte Reaction.- Role of a Serum Component in Regulating the Growth of a Murine Lymphoma.- IV. Special Procedures in Cancer Therapy — Effects on the Immune Status.- Influence of Hyperthermia on the Immune Status: Experimental Basis and Clinical Application in Cancer Patients.- Immunologic Phenomena Induced by Hyperthermia in Normal and Tumor-Bearing Hosts and Their Relevance for Cancer Therapy.- Discussion.- Immunologic Phenomena Induced by Cryosurgery.- Clinical and Immunologic Results of Cryosurgery in Patients With Rectal Cancer.- Parenteral Hyperalimentation as an Adjunct to Cancer Therapy in Patients with Colorectal Tumors.- Discussion.- V. Summing Up.- Summing Up.